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Figure 1 | Arthritis Research & Therapy

Figure 1

From: The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

Figure 1

Immunohistochemical studies showing the localisation of interleukin (IL)-4 receptor (IL-4R), IL-common γ receptor (IL-cγR) and IL-13 receptor (IL-13R) in the human intervertebral disc. IL-4R immunopositivity in nondegenerative samples of (a) annulus fibrosus (AF) cells and (d) nucleus pulposus (NP) cells. IL-cγR immunopositivity in nondegenerative samples of (b) AF cells and (e) NP cells. IL-13R immunonegativity in nondegenerative samples of (c) AF cells and (f) NP cells. (g) A positive control slide is included for IL-13R in nondegenerative articular chondrocytes. Scale bar, 25 μm.

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