Mannose-binding lectin does not explain the course and outcome of pregnancy in rheumatoid arthritis

Table 3 Regression analysis of mannose-binding lectin genotype groups and pregnancy outcome measures based on dichotomous variables^a

	MBL genotype groups A, B and C (three strata)			MBL genotype group A vs. B plus C (dichotomous)
Variable stratified	OR	95% CI	n	OR	95% CI	n
Miscarriage
No correction	1.13	0.64 to 1.99	21/205	1.31	0.53 to 3.23	21/205
Correction for all confounders	0.99	0.53 to 1.83	20/178	1.12	0.43 to 2.87	20/178
Hypertension
No correction	0.93	0,53 to 1.66	23/174	0.72	0.30 to 1.78	23/174
Correction for all confounders	0.76	0.36 to 1.61	16/127	0.58	0.18 to 1.83	16/127
Gestational age (<37 wk)
No correction	1.30	0.68 to 2.58	14/157	1.20	0.40 to 3.60	14/157
Correction for all confounders	2.12	0.80 to 5.60	13/127	2.38	0.47 to 12.1	13/127
Low birth weight (<2,500 g)
No correction	0.93	0.40 to 2.28	10/158	0.76	0.21 to 2.82	10/158
Correction for all confounders	0.92	0.30 to 2.90	9/127	0.87	0.14 to 5.38	9/127

^aDichotomous variable outcome measures include miscarriage, hypertension, gestational age and low birth weight in patients with rheumatoid arthritis. MBL, mannose-binding lectin; A, B and C, MBL production genotype groups A (high), B (intermediate) and C (low); OR, odds ratio; 95% CI, 95% confidence interval.