Anti-CCP antibody
|
Sensitivity
|
Sensitivity
|
Specificity
|
---|
|
pre-patients
|
patients
| |
IgGP
|
33.8***
|
71.7***
|
98.9
|
IgAP
|
23.9***
|
43.3***
|
97.1
|
IgMaP
|
11.8
|
32.8***
|
93.9
|
IgGE
|
32.4***
|
71.2***
|
98.5
|
- The cut-off values for positivity for the antibodies were calculated using ROC curves
- aAnalysis of IgM in pre-patients; n = 68, in patients; n = 58, and controls; n = 263, E analysed with a kit from Euro-Diagnostica, P analysed with a kit from Phadia.***P < 0.001. Anti-CCP, anti-cyclic citrullinated peptide; ROC, receiver operating characteristic; Ig, immunoglobulin.