Anti-CCP antibody | Sensitivity | Sensitivity | Specificity |
---|
| pre-patients | patients | |
IgGP | 33.8*** | 71.7*** | 98.9 |
IgAP | 23.9*** | 43.3*** | 97.1 |
IgMaP | 11.8 | 32.8*** | 93.9 |
IgGE | 32.4*** | 71.2*** | 98.5 |
- The cut-off values for positivity for the antibodies were calculated using ROC curves
- aAnalysis of IgM in pre-patients; n = 68, in patients; n = 58, and controls; n = 263, E analysed with a kit from Euro-Diagnostica, P analysed with a kit from Phadia.***P < 0.001. Anti-CCP, anti-cyclic citrullinated peptide; ROC, receiver operating characteristic; Ig, immunoglobulin.