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Table 1 Positions of the named susceptibility loci from murine genome studies involving NZB, NZW, NZM2410, BXSB, and MRL/lpr mice (Wakeland et al, 1999) [2].

From: Genetic epidemiology: Systemic lupus erythematosus

Chromosome

 

location

Susceptibility loci

1

Bxs1, Bxs2, Sbw1, Gld, Sle1, Nba2, Lbw7, Bxs3

3

Sles3 *

4

Sle2, Sbw2, Lbm1, nba1, Lbw2, Lmb1, Sles2 *

5

Sle6, Lmb2, Lbw3

6

Lbw4

7

Lrdm1, Sle5, Sle3, Lbw5, Lmb3, Nba3

9

Sles4 *

10

Lmb4

11

Lbw8

12

Lrdm2

17

H2d/z, Sle4, Sles1 *

18

Lbw6

19

Fas

  1. *Suppressive modifiers, responsible for the suppression of fatal disease in the NZW genome.