Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis

Table 1 SSc patient and normal volunteer characteristics

	SSc patients	Normal volunteers
Age (years)	52.5 ± 1.8^a	51.2 ± 4.4
Women	18	3
Men	2	7
Diffuse SSc	19	NA^b
Raynaud's	19	NA
Disease duration (years)	3.7 ± 0.8	NA
Early disease^c	13	NA
Late disease	7	NA
Deceased	4	NA
Renal involvement	1	NA
Interstitial lung disease	10	NA
Pulmonary arterial hypertension	2	NA
Digital ulcers	10	NA
Gastrointestinal disease	19	NA
Gastric antral vascular ectasia	3	NA
Immunomodulatory therapy	3	NA
SSc patients serum CXCL16 (ng/ml)
	With	Without
Pulmonary arterial hypertension	5.7 ± 1.2 (n = 2)^d	4.5 ± 0.1 (n = 18)
Early disease	4.9 ± 0.2 (n = 13)^d	4.0 ± 0.1 (n = 7)
Deceased	5.6 ± 0.4 (n = 4)^d	4.4 ± 0.1 (n = 16)

^aMean ± SEM. ^bNA = Not applicable. ^cEarly disease = less than five years. ^dP < 0.05.

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