| Radiographic OA | Pain | Mean | SE | 95% CI of the mean | P-value | 95% CI for difference | |
---|---|---|---|---|---|---|---|---|
 |  |  |  |  | Lower | Upper |  |  |
sC2C | K/L 1 | - | 5.49 | 0.04 | 5.40 | 5.57 | 0.02* | -0.19 to -0.04 |
Ln (pmol/ml) | Â | + | 5.75 | 0.07 | 5.61 | 5.91 | Â | Â |
 | K/L 2 | - | 5.43 | 0.07 | 5.29 | 5.57 | 1.00 | -0.36 to 0.35 |
 |  | + | 5.44 | 0.11 | 5.21 | 5.66 |  |  |
sCPII | K/L 1 | - | 7.38 | 0.07 | 7.24 | 7.52 | 0.01* | -0.83 to -0.10 |
Ln (ng/ml) | Â | + | 7.84 | 0.11 | 7.62 | 8.07 | Â | Â |
 | K/L 2 | - | 7.05 | 0.11 | 6.83 | 7.28 | 1.00 | -0.44 to 0.71 |
 |  | + | 6.92 | 0.18 | 6.56 | 7.28 |  |  |
uCTX-II/Cr | K/L 1 | - | 5.04 | 0.14 | 4.76 | 5.32 | 0.07 | -1.48 to 0.03 |
Ln (ng/μmol creatinine) |  | + | 5.77 | 0.22 | 5.32 | 6.22 |  |  |
 | K/L 2 | - | 5.38 | 0.23 | 4.92 | 5.83 | <0.05* | -2.36 to -0.05 |
 |  | + | 6.56 | 0.36 | 5.82 | 7.29 |  |  |
sC2C | K/L 1 | - | 0.15 | 0.03 | 0.10 | 0.20 | 1.00 | -1.12 to 0.17 |
/sCPII | Â | + | 0.12 | 0.04 | 0.04 | 0.21 | Â | Â |
 | K/L 2 | - | 0.27 | 0.04 | 0.19 | 0.36 | 1.00 | -0.17 to 0.26 |
 |  | + | 0.23 | 0.07 | 0.09 | 0.37 |  |  |
uCTX-II/sCPII | K/L 1 | - | 0.09 | 0.06 | -0.03 | 0.22 | 1.00 | -0.39 to 0.29 |
 |  | + | 0.14 | 0.10 | -0.06 | 0.35 |  |  |
 | K/L 2 | - | 0.42 | 0.10 | 0.21 | 0.63 | <0.05* | -1.07 to 0 |
 |  | + | 0.95 | 0.17 | 0.62 | 1.29 |  |  |
uNTX/Cr | K/L 1 | - | 3.71 | 0.11 | 3.48 | 3.93 | 1.00 | -0.89 to 0.33 |
Ln (ng/ml creatinine) | Â | + | 3.99 | 0.18 | 3.62 | 4.35 | Â | Â |
 | K/L 2 | - | 3.33 | 0.18 | 2.96 | 3.70 | 0.73 | -1.49 to 0.41 |
 |  | + | 3.87 | 0.29 | 3.27 | 4.47 |  |  |
sHA | K/L 1 | - | 2.77 | 0.13 | 2.51 | 3.03 | 0.06 | -1.40 to 0.01 |
Ln (pmol/ml) | Â | + | 3.46 | 0.21 | 3.04 | 3.89 | Â | Â |
 | K/L 2 | - | 3.66 | 0.21 | 3.24 | 4.09 | 1.00 | -1.42 to 0.78 |
 |  | + | 3.98 | 0.34 | 3.29 | 4.67 |  |  |