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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Figure 3

Transforming growth factor beta differential effects on matrix genes and Sox9 according to treatment duration. Human articular chondrocytes (HAC) were cultured and incubated as Figure 2. COL1A1, COL2A1, COL10A1, aggrecan and Sox9 mRNA levels were then determined by RT-PCR. C, control. *, P < 0.05, **, P < 0.01, ***, P < 0.001.

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