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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Figure 4

Transforming growth factor beta 1 (TGFβ1) enhances TGFβ receptors mRNA turnover. Subconfluent human articular chondrocytes (HAC) were incubated with DMEM + 2% FCS for 24 hours. Thereafter, transforming growth factor beta 1 (TGFβ1) or vehicle were added in the presence of actinomycin D (10 μg/ml). Cells were then harvested at the indicated times for RT-PCR.

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