Figure 2From: Articular cartilage and changes in Arthritis: Matrix degradationSchematic representation of the domain structure of ADAMTS members involved in aggrecan degradation. The conserved HEXXH motif is as in Figure 1. ADAMTS-4 and -5, aggrecanase-1 and -2; ADAMTS-1, also termed METH-1 (metalloprotease and thrombospondin domains).Back to article page