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Table 3 Duration in years of the various antibodies preceding the onset of symptoms and diseasea

From: Autoantibodies predate the onset of systemic lupus erythematosus in northern Sweden

Antibody Number of positive test results Interval between positive test and onset of symptoms, mean (SD) Interval between positive test and diagnosis, mean (SD)
Ro/SSA 7 6.6 (2.5) 8.1 (2.3)
RNP 4 5.9 (2.5) 7.5 (2.5)
Histones 5 5.0 (1.5) 6.5 (1.9)
ANA 16 4.1 (0.8) 7.5 (1.2)
La/SSB 3 4.0 (1.0) 7.0 (0.6)
dsDNA 7 3.6 (1.2) 6.6 (2.0)
Jo-1 3 2.4 (1.1) 3.1 (1.1)
Scl-70 2 1.4 (0.6) 2.1 (0.9)
Sm 1 0.7 1.1
Centromere protein B 1 0.2 6.6
  1. ANA, antinuclear antibody; aRo/SSA, anti-Sjögren's syndrome antigen A; dsDNA, double-stranded DNA; Jo-1, anti-histidyl-tRNA synthetase antibody; La/SSB, anti-Sjögren's syndrome antigen B; RNP, ribonucleoprotein; Scl-70, scleroderma 70; SD, standard deviation; Sm, Smith.