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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

Figure 1

Pam3CSK4 induced IL-6 and IL-8 in mononuclear cells from RA patients. SFMCs (A; n = 6) and PBMCs (B; n = 11) were stimulated with TLR2 agonist Pam3CSK4 at 200 ng/ml. Levels of IL-6 and IL-8 in the culture supernatants were determined and compared to unstimulated cells (Basal) at six hours. Values are expressed as the mean ± SEM. * P < 0.05, significantly different from control as determined using Wilcoxon Signed Rank analysis.

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Arthritis Research & Therapy

ISSN: 1478-6362

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