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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Canakinumab (ACZ885, a fully human IgG1 anti-IL-1β mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)

Figure 3

Response pattern in three patients: physician global assessment, physician skin assessment and CRP and SAA levels. In the upper and middle panels, the squares represent the physician's assessment of global disease activity and rash. The shaded areas indicate absent and mild severity. In the lower panel, the concentrations of CRP (solid line, circle) and SAA (dotted line, triangle) are presented. The shaded area indicates a concentration of 0 to 30 mg/L. Vertical dotted lines on all panels indicate the time of re-dosing.

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