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Table 4 Histological characteristics of patients with lSSc and controlsa

From: Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study

  Upper inner arm  
Histological characteristics lSSc (n= 7) Controls (n= 18) Pvalue
Mean epidermal pigmentation (± SD) 22 ± 23 16 ± 20 0.532
Mean hyalinised collagen (± SD) 2.3 ± 2.4 2.1 ± 1.9 0.893
Myofibroblast score (± SD) 0 ± 0 0 ± 0 NRb
Mean epidermal thickness (± SD) 0.86 ± 0.48 0.92 ± 0.31 0.714
Mononuclear cellular infiltration (± SD) 1.3 ± 1.1 1.5 ± 0.8 0.650
Mucine deposition in deep dermis (± SD) 1.2 ± 0.49 1.3 ± 0.7 0.663
Entrapment of eccrine sweat gland, n (%) 3 (43) 1/13 (7.7) 0.101
Focal exocytosis, n (%) 2 (29) 5/17 (16) 1.0
Loss of adnexae, n (%) 1 (14) 7 (50) 0.174
Loss of epidermal papillae, n (%) 2 (29) 2 (11) 0.548
Intima proliferation of deep arterioles, n (%) 0 (0) 0 (0) NRb
Parakeratosis, n (%) 0 (0) 0 (0) NRb
Pigment incontinence, n (%) 1 (14) 3 (17) 1.0
Telangiectasia in papillary dermis, n (%) 1 (14) 1 (5.6) 0.490
  1. alSSc, limited systemic sclerosis; NR, not reported; bstatistical testing could not be performed.