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Table 4 Histological characteristics of patients with lSSc and controlsa

From: Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study

 

Upper inner arm

 

Histological characteristics

lSSc

(n= 7)

Controls (n= 18)

Pvalue

Mean epidermal pigmentation (± SD)

22 ± 23

16 ± 20

0.532

Mean hyalinised collagen (± SD)

2.3 ± 2.4

2.1 ± 1.9

0.893

Myofibroblast score (± SD)

0 ± 0

0 ± 0

NRb

Mean epidermal thickness (± SD)

0.86 ± 0.48

0.92 ± 0.31

0.714

Mononuclear cellular infiltration (± SD)

1.3 ± 1.1

1.5 ± 0.8

0.650

Mucine deposition in deep dermis (± SD)

1.2 ± 0.49

1.3 ± 0.7

0.663

Entrapment of eccrine sweat gland, n (%)

3 (43)

1/13 (7.7)

0.101

Focal exocytosis, n (%)

2 (29)

5/17 (16)

1.0

Loss of adnexae, n (%)

1 (14)

7 (50)

0.174

Loss of epidermal papillae, n (%)

2 (29)

2 (11)

0.548

Intima proliferation of deep arterioles, n (%)

0 (0)

0 (0)

NRb

Parakeratosis, n (%)

0 (0)

0 (0)

NRb

Pigment incontinence, n (%)

1 (14)

3 (17)

1.0

Telangiectasia in papillary dermis, n (%)

1 (14)

1 (5.6)

0.490

  1. alSSc, limited systemic sclerosis; NR, not reported; bstatistical testing could not be performed.