From: Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study
 | Upper inner arm |  | |
---|---|---|---|
Histological characteristics | lSSc (n= 7) | Controls (n= 18) | Pvalue |
Mean epidermal pigmentation (± SD) | 22 ± 23 | 16 ± 20 | 0.532 |
Mean hyalinised collagen (± SD) | 2.3 ± 2.4 | 2.1 ± 1.9 | 0.893 |
Myofibroblast score (± SD) | 0 ± 0 | 0 ± 0 | NRb |
Mean epidermal thickness (± SD) | 0.86 ± 0.48 | 0.92 ± 0.31 | 0.714 |
Mononuclear cellular infiltration (± SD) | 1.3 ± 1.1 | 1.5 ± 0.8 | 0.650 |
Mucine deposition in deep dermis (± SD) | 1.2 ± 0.49 | 1.3 ± 0.7 | 0.663 |
Entrapment of eccrine sweat gland, n (%) | 3 (43) | 1/13 (7.7) | 0.101 |
Focal exocytosis, n (%) | 2 (29) | 5/17 (16) | 1.0 |
Loss of adnexae, n (%) | 1 (14) | 7 (50) | 0.174 |
Loss of epidermal papillae, n (%) | 2 (29) | 2 (11) | 0.548 |
Intima proliferation of deep arterioles, n (%) | 0 (0) | 0 (0) | NRb |
Parakeratosis, n (%) | 0 (0) | 0 (0) | NRb |
Pigment incontinence, n (%) | 1 (14) | 3 (17) | 1.0 |
Telangiectasia in papillary dermis, n (%) | 1 (14) | 1 (5.6) | 0.490 |