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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature

Figure 4

Changes in clinical arthritis scores in mice with collagen-induced arthritis after treatment with peptides or the vehicle. Mice were injected intravenously on days 35 and 41 with either the targeted proapoptotic chimeric peptide RGD-4C-D(KLAKLAK)2 or a mixture of the uncoupled peptides RGD-4C and D(KLAKLAK)2 or the vehicle. Clinical arthritis scores were evaluated using a scale of 0 to 4+ for each paw (maximum = 16). The mean pretreatment score was 10.3 ± 0.5.

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