Skip to main content

Table 3 Independent effect of intron 2 SNPs in the carriers of the 3' UTR risk genotypesa

From: TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study

Risk genotype

Study group, n(%)

   

rs3853839

rs179019

rs179010

SLE (N= 322)

Controls (N= 243)

P

OR

95% CI

G/G or G/C

A/A

T/T

42 (13.0)

14 (5.8)

   

+

+

+

280 (87.0)

229 (94.2)

0.0043

2.45

1.31 to 4.60

+

Others

   

Reference

 
  1. aSNP, single-nucleotide polymorphism; 3' UTR, 3' untranslated region; OR, odds ratio; 95% CI, 95% confidence interval. Genotype frequencies are shown in parentheses (%). P value was calculated using Fisher's exact test.
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us