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Table 1 Mutational frequency of the nonproductive and productive Vλ repertoires of the patient with systemic lupus erythematosus (SLE) and normal subjects

From: Perturbations in the impact of mutational activity on Vλ genes in systemic lupus erythematosus

  Patient with SLE Normal subjects
  Nonproductive Productive Χ2P < Nonproductive Productive Χ2P <
Number of Vλ nucleotides 16679 28496   12679 39225 0.001
Number of Vλ nucleotides in 13194 23819   6339 21821 0.001
mutated rearrangements       
Number of mutations 412 807   76 440  
Mutational frequency of all 2.5 2.8 0.022 0.60 1.12 0.001
VλJλ gene rearrangements (%)       
Mutational frequency of mutated 3.1 3.4 NS 1.19 2.02 0.001
VλJλ gene rearrangements (%)       
  1. J = joining [region]; NS = not significant; V = variable [region].