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Table 2 Distribution of phenotypic frequencies of HLA- A alleles

From: Associations between the HLA-Apolymorphism and the clinical manifestations of Behcet's disease

  All subjects OR (95% CI) P
(Pc)
HLA-B*51non-carriers OR (95% CI) P
(Pc)
HLA-B*51carriers OR (95% CI) P
(Pc)
  BD
N= 223
Control
N= 1,398
   BD
N= 142
Control
N= 1,116
   BD
N= 81
Control
N= 282
  
A*01:01 2 (0.9) 45 (3.2) 0.27
(0.07 to 1.13)
  2 (1.4) 38 (3.4) 0.41
(0.10 to 1.70)
  0 (0.0) 7 (2.5) NA  
A*02:01 77 (34.5) 433 (31.0) 1.18
(0.87 to 1.58)
  46 (32.4) 359 (32.2) 1.01
(0.70 to 1.47)
  31 (38.3) 74 (26.2) 1.74
(1.04 to 2.93)
0.035
(> 1.0)
A*02:03 4 (1.8) 19 (1.4) 1.33
(0.45 to 3.93)
  3 (2.1) 19 (1.7) 1.25
(0.36 to 4.26)
  1 (1.2) 0 (0.0) NA  
A*02:05 0 (0.0) 1 (0.1) NA   0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA  
A*02:06 35 (15.7) 250 (17.9) 0.85
(0.58 to 1.26)
  18 (12.7) 193 (17.3) 0.69
(0.41 to 1.17)
  17 (21.0) 57 (20.2) 1.05
(0.57 to 1.93)
 
A*02:07 27 (12.1) 89 (6.4) 2.03
(1.28 to 3.20)
0.002
(0.06)
19 (13.4) 80 (7.2) 2.00
(1.17 to 3.41)
0.010
(> 1.0)
8 (9.9) 9 (3.2) 3.32
(1.24 to 8.92)
0.031
(> 1.0)
A*02:10 0 (0.0) 13 (0.9) NA   0 (0.0) 12 (1.1) NA   0 (0.0) 1 (0.4) NA  
A*03:01 3 (1.4) 35 (2.5) 0.53
(0.16 to 1.74)
  3 (2.1) 28 (2.5) 0.84
(0.25 to 2.79)
  0 (0.0) 7 (2.5) NA  
A*03:02 1 (0.5) 6 (0.4) 1.05
(0.13 to 8.72)
  1 (0.7) 5 (0.5) 1.58
(0.18 to 13.59)
  0 (0.0) 1 (0.4) NA  
A*11:01 39 (17.5) 242 (17.3) 1.01
(0.70 to 1.47)
  25 (17.6) 188 (16.9) 1.05
(0.67 to 1.67)
  14 (17.3) 54 (19.2) 0.88
(0.46 to 1.69)
 
A*11:02 2 (0.9) 2 (0.1) 6.32
(0.89 to 45.08)
  1 (0.7) 1 (0.1) 7.91
(0.49 to 127 to 13)
  1 (1.2) 1 (0.4) 3.5
(0.22 to 56.58)
 
A*24:02 95 (42.6) 578 (41.3) 1.05
(0.79 to 1.40)
  54 (38.0) 442 (39.6) 0.94
(0.65 to 1.34)
  41 (50.6) 136 (48.2) 1.10
(0.67 to 1.80)
 
A*24:03 0 (0.0) 1 (0.1) NA   0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA  
A*24:04 0 (0.0) 1 (0.1) NA   0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA  
A*24:08 0 (0.0) 1 (0.1) NA   0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA  
A*24:20 1 (0.5) 2 (0.1) 3.14
(0.28 to 34.82)
  1 (0.7) 2 (0.2) 3.95
(0.36 to 43.84)
  0 (0.0) 0 (0.0) NA  
A*26:01 26 (11.7) 93 (6.7) 1.85
(1.17 to 2.93)
0.008
(0.24)
19 (13.4) 74 (6.6) 2.18
(1.27 to 3.72)
0.004
(0.12)
7 (8.6) 19 (6.7) 1.31
(0.53 to 3.23)
 
A*26:02 11 (4.9) 58 (4.2) 1.20
(0.62 to 2.32)
  7 (4.9) 46 (4.1) 1.21 (0.53 to 2.73)   4 (4.9) 12 (4.3) 1.17
(0.37 to 3.72)
 
A*26:03 7 (3.1) 17 (1.2) 2.63
(1.08 to 6.42)
0.037
(> 1.0)
5 (3.5) 14 (1.3) 2.87
(1.02 to 8.10)
0.053 2 (2.5) 3 (1.1) 2.35
(0.39 to 14.34)
 
A*26:05 0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA   0 (0.0) 1 (0.4) NA  
A*26:18 0 (0.0) 1 (0.1) NA   0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA  
A*29:01 2 (0.9) 28 (2.0) 0.44
(0.10 to 1.87)
  2 (1.4) 24 (2.2) 0.65
(0.15 to 2.78)
  0 (0.0) 4 (1.4) NA  
A*29:02 1 (0.5) 0 (0.0) NA   1 (0.7) 0 (0.0) NA   0 (0.0) 0 (0.0) NA  
A*30:01 8 (3.6) 74 (5.3) 0.67
(0.32 to 1.40)
  7 (4.9) 63 (5.7) 0.87
(0.39 to 1.93)
  1 (1.2) 11 (3.9) 0.31
(0.04 to 2.42)
 
A*30:04 12 (5.4) 31 (2.2) 2.51
(1.27 to 4.96)
0.006
(0.18)
11 (7.8) 26 (2.3) 3.52
(1.70 to 7.29)
0.002
(0.06)
1 (1.2) 5 (1.8) 0.69
(0.08 to 6.01)
 
A*31:01 22 (9.9) 160 (11.4) 0.85
(0.53 to 1.35)
  10 (7.0) 98 (8.8) 0.79
(0.40 to 1.55)
  12 (14.8) 62 (22.0) 0.62
(0.31 to 1.21)
 
A*31:11 0 (0.0) 1 (0.1) NA   0 (0.0) 0 (0.0) NA   0 (0.0) 1 (0.4) NA  
A*32:01 0 (0.0) 26 (1.9) NA   0 (0.0) 25 (2.2) NA   0 (0.0) 1 (0.4) NA  
A*33:03 43 (19.3) 405 (29.0) 0.59
(0.41 to 0.83)
0.003
(0.09)
33 (23.2)† 345 (30.9) 0.68
(0.45 to 1.02)
  10 (12.4) 60 (21.3) 0.52
(0.25 to 1.07)
 
A*68:01 1 (0.5) 3 (0.2) 2.09
(0.22 to 20.23)
  1 (0.7) 2 (0.2) 3.95
(0.36 to 43.85)
  0 (0.0) 1 (0.4) NA  
  1. Values are presented as N (%). P (Pc) values are presented for those alleles with estimable OR (95% CI) and P-values of < 0.05.
  2. P = 0.047 (HLA-B*51 negative vs. positive patients). BD, Behcet's disease; CI, confidence intervals; NA, not applicable; OR, odds ratio; Pc, corrected P