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Table 3 Meta-analysis on the association between HLA- A alleles and BD†

From: Associations between the HLA-Apolymorphism and the clinical manifestations of Behcet's disease

Allele Total subjects HLA-B*51 non-carriers
  OR (95% CI) P I2
(%)
P het Weight
(%)
OR (95% CI) P I2
(%)
P het Weight
(%)
A*01:01 0.54 (0.21 to 1.42) 0.21 76 0.04 92.7 0.65 (0.22 to 1.91) 0.43 60 0.11 92.7
A*02:01 1.20 (0.97 to 1.48) 0.09 0 0.70 65.7 1.13 (0.87 to 1.47) 0.37 0 0.33 70.5
A*02:03 0.96 (0.35 to 2.65) 0.93 27 0.24 67.5 0.99 (0.32 to 3.09) 0.99 0 0.47 70.9
A*02:06 0.86 (0.66 to 1.13) 0.28 0 0.69 58.2 0.73 (0.50 to 1.06) 0.10 0 0.62 60.7
A*02:07 1.96 (1.34 to 2.85) 0.0005 0 0.62 66.6 2.00 (1.30 to 3.09) 0.002 0 0.69 69.7
A*02:10 0.37 (0.06 to 2.37) 0.30 0 0.43 80.0 0.37 (0.05 to 3.05) 0.36 0 0.72 74.5
A*03:01 0.44 (0.15 to 1.26) 0.13 0 0.56 71.1 0.77 (0.26 to 2.21) 0.62 0 0.84 75.7
A*03:02 0.71 (0.12 to 4.21) 0.70 0 0.56 52.4 1.12 (0.18 to 6.77) 0.90 0 0.64 51.9
A*11:01 0.78 (0.60 to 1.03) 0.08 77 0.04 50.5 0.85 (0.61 to 1.19) 0.35 51 0.15 50.6
A*11:02 1.30 (0.30 to 5.57) 0.73 75 0.05 18.0 1.23 (0.20 to 7.71) 0.82 57 0.13 11.5
A*24:02 0.89 (0.75 to 1.05) 0.18 44 0.18 47.0 0.83 (0.67 to 1.03) 0.10 0 0.43 48.8
A*24:20 0.60 (0.13 to 2.83) 0.52 59 0.12 12.1 0.68 (0.12 to 3.73) 0.65 63 0.10 12.6
A*26:01 1.89 (1.41 to 2.53) <0.0001 0 0.91 38.9 2.42 (1.73 to 3.39) <0.00001 0 0.62 41.3
A*26:02 1.48 (0.90 to 2.42) 0.12 7 0.30 64.5 1.93 (1.09 to 3.40) 0.02 69 0.07 69.1
A*26:03 2.01 (1.14 to 3.56) 0.02 0 0.51 28.4 2.40 (1.17 to 4.91) 0.02 0 0.70 36.6
A*26:05 3.69 (0.44 to 31.24) 0.23 0 0.69 45.3 NA     
A*31:01 1.22 (0.91 to 1.62) 0.18 79 0.03 51.9 0.73 (0.45 to 1.19) 0.21 0 0.76 51.8
A*33:03 0.52 (0.39 to 0.70) <0.00001 64 0.09 71.0 0.58 (0.41 to 0.81) 0.001 67 0.08 71.3
  1. †Genetic data were pooled using allelic frequency.
  2. CI, confidence interval; I2, between-study heterogeneity; NA, not applicable; OR, odds ratios for the risk to develop BD; P, P-values for significance of each HLA-A allele in the pooled genetic effect (calculated by Mantel-Haenszel fixed method); Phet, P values for heterogeneity statistics; weight (%), weight of the present study.