Skip to main content

Table 2 Synovial fluid concentrations of the biological markers in patients with OA or RA and in asymptomatic organ donorsa

From: The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors

    

P values

Marker

Donor (n = 20)

OA (n = 45)

RA (n = 22)

OA vs. donor

RA vs. donor

OA vs. RA

IL-6, pg/mL

86.97 (82.0)

119.4 (193.2)

354.7 (1851.6)

0.4

0.0011

0.0026

IL-8, pg/mL

451 (170.7)

429 (87.3)

583.6 (1086.4)

0.0809

0.016

<0.0001

IL-11, pg/mL

211.6 (40.8)

296.2 (257.2)

217.5 (178)

0.0067

0.4557

0.2393

IL-1, pg/mL

9.08 (1.6)

7.76 (2.6)

9.26 (11.1)

0.02

0.9318

0.0497

OP-1, ng/mL

54.49 (29.3)

81.79 (116.0)

167.1 (194.8)

<0.0001

<0.0001

0.0013

LIF, pg/mL

228.5 (131.6)

107.5 (136.9)

128.4 (222.7)

0.0063

0.139

0.1991

Osteo, ng/mL

2.58 (6.6)

2.515 (4.9)

1.99 (3.9)

0.7437

0.893

0.5384

COMP, U/L

413.2 (339.9)

490.2 (207.5)

507.3 (352.9)

0.4652

0.3102

0.3865

  1. aOA, osteoarthritis; RA, rheumatoid arthritis; IL, interleukin; OP-1, osteogenic protein 1; LIF, leukemia-inhibitory factor; Osteo, osteocalcin; COMP, cartilage oligomeric protein. Absolute values of biomarkers detected in synovial fluid of patients with osteoarthritis, rheumatoid arthritis and asymptomatic organ donors. P values were calculated by using an unpaired, two-tailed Mann-Whitney t-test with 95% confidence interval. Values are expressed as medians (interquartile ranges).