The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors

Table 3 Spearman's rank correlation coefficients for RA study population^a

	IL-1	IL-6	IL-8	IL-11	LIF	Osteocalcin	COMP	OP-1
IL-1	1.0000
IL-6	ρ = 0.3643 P = 0.0801	1.0000
IL-8	ρ = 0.5174 P = 0.0096	ρ = 0.8643 P = 0.001	1.0000
IL-11	ρ = -0.2278 P = 0.2843	ρ = -0.1530 P = 0.4753	ρ = -0.0626 P = 0.7713	1.0000
LIF	ρ = -0.1802 P = 0.3996	ρ = 0.2733 P = 0.1963	ρ = 0.3803 P = 0.0667	ρ = 0.2124 P = 0.3191	1.0000
Osteocalcin	ρ = -0.0670 P = 0.7559	ρ = 0.1878 P = 0.3795	ρ = 0.1670 P = 0.4355	ρ = 0.3783 P = 0.0684	ρ = 0.5927 P = 0.0023	1.0000
COMP	ρ = 0.3009 P = 0.1531	ρ = 0.0991 P = 0.6449	ρ = 0.0548 P = 0.7993	ρ = -0.2009 P = 0.3466	ρ = -0.3307 P = 0.1145	ρ = -0.0548 P = 0.7993	1.0000
OP-1	ρ = 0.5791 P = 0.0030	ρ = 0.2896 P = 0.1699	ρ = 0.4130 P = 0.0448	ρ = -0.1896 P = 0.3750	ρ = 0.1897 P = 0.3746	ρ = 0.1817 P = 0.3954	ρ = 0.1922 P = 0.3683	1.000

^aRA, rheumatoid arthritis; IL, interleukin; LIF, leukemia-inhibitory factor; COMP, cartilage oligomeric protein; OP-1, osteogenic protein 1. Spearman's rank correlation coefficients (IL-1, IL-6, IL-8, IL-11, LIF, osteocalcin, COMP and OP-1) for the RA cohort are expressed as Spearman's ρ and P values. A total of 22 RA patients were sampled, five male and seventeen female.

ISSN: 1478-6362