Skip to main content

Advertisement

Table 1 The frequency and severity of arthritis triggered by intra-articular injection of 100 µg of peptidoglycan in mice depleted of neutrophils, NK cells, or monocytes

From: Staphylococcal peptidoglycans induce arthritis

Group Mice Incidence Severity
RB6-8C5 BALB/c 10/10 2.0 ± 0.7
Control BALB/c 9/9 2.3 ± 0.8
PK136 C57BL/6 10/10 1.8 ± 0.8
Control C57BL/6 10/10 2.2 ± 0.6
Etoposide C57BL/6 8/8 1.6 ± 0.7
Control C57BL/6 10/10 2.1 ± 0.5
SCID CB17 9/9 1.6 ± 0.7
Control CB17 10/10 2.7 ± 0.5
  1. RB6-8C5 is an IgG2b antibody that depletes neutrophils in BALB/c mice. Etoposide is a cytotoxic drug that selectively depletes monocytes. PK136 is an IgG2a antibody that depletes natural killer cells. SCID mice lack T and B cells.