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Table 7 Changes in the expression of TGF-β/BMP family related genes, their receptors, and signaling regulators

From: Regulation of chondrocyte gene expression by osteogenic protein-1

  rhOP-1 vs Cntr rhOP-1AS vs Cntr  
  fold change fold change Accession no.
GDF-15 3.04↓ 2.03↑ [GenBank:NM_004864]
BMP-2 2.67↓   [GenBank:NM_001200]
Inhibin-βa (activin A) 2.32↓ 2.15↑ [GenBank:NM_002192]
BMP-2 inducible kinase 1.61↓   [GenBank:NM_017593]
Parathyroid hormone-like hormone 1.60↓ 2.17↑ [GenBank:NM_002820]
ID2   2.32↓ [GenBank:NM_002166]
Notch 4   2.32↓ [GenBank:NM_004557]
MAD-6   2.05↓ [GenBank:NM_005585]
Gremlin 1.88↑ 1.94↓ [GenBank:NM_013372]
GDF-10   1.86↓ [GenBank:NM_004962]
ID4 1.82↑ 1.84↓ [GenBank:NM_001546]
ID3   1.73↓ [GenBank:NM_002167]
MAD interacting protein   1.69↓ [GenBank:NM_004799]
MAD-4   1.67↓ [GenBank:NM_005359]
Notch 1   1.65↓ [GenBank:NM_017617]
MAD-7   1.62↓ [GenBank:NM_005904]
TGF-α   1.54↓  
Receptors    
Frizzled homolog 10 (Drosophila) 1.57↓   [GenBank:NM_007197]
Activin-α RI 1.53↓   [GenBank:NM_001105]
Activin A-RIIB   2.42↓ [GenBank:NM_001106]
BMPR1A   1.83↓ [GenBank:NM_004329]
TGF-βRI   1.51↓ [GenBank:NM_004612]
TGF-βRIII   1.50↓ [GenBank:NM_003243]
TGF-β R2 1.58↑   [GenBank:NM_003242]
Activin A-RIB   1.53↑ [GenBank:NM_004302]
Bone formation    
Osteomodulin 1.78↑ 2.56↓ [GenBank:NM_005014]