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Table 9 Changes in the expression of matrix proteins, their receptors, and integrins

From: Regulation of chondrocyte gene expression by osteogenic protein-1

  rhOP-1 vs Cntr OP-1AS vs Cntr  
  fold change fold change Accession no.
Matrix proteins    
Collagen IV-α3 1.82↓ 1.54↓ [GenBank:NM_000091]
Laminin-β1 1.65↓ 3.38↓ [GenBank:NM_002291]
Chondroitin sulfate PG6 (bamacan) 1.60↓ 1.52↑ [GenBank:NM_005445]
Versican (chondroitin sulfate PG2)   2.98↓ [GenBank:NM_004385]
Collagen I-α1   2.63↓ [GenBank:NM_000088]
Collagen XIV-α1   2.59↓ [GenBank:NM_021110]
Collagen I-α2   2.57↓ [GenBank:NM_000089]
Cartilage associated protein   2.13↓ [GenBank:NM_006371]
Cadherin 11 (OB-cadherin (osteoblast))   2.03↓ [GenBank:NM_001797]
Collagen XVI-α1   2.00↓ [GenBank:NM_001856]
Dermatan Sulfate PG3 1.57↑ 1.95↓ [GenBank:NM_004950]
Collagen V-α1   1.89↓ [GenBank:NM_000093]
Bone sialoprotein   1.83↓ [GenBank:NM_004967]
Collagen VIII-α2   1.73↓ [GenBank:NM_005202]
Collagen VI-α1   1.70↓ [GenBank:NM_001848]
Collagen IV-α1   1.70↓ [GenBank:NM_001845]
Collagen IV-α2   1.69↓ [GenBank:NM_001846]
Syndecan 1.58↑ 1.67↓ [GenBank:NM_002997]
Collagen V-α2   1.65↓ [GenBank:NM_000393]
Osteonectin   1.51↓ [GenBank:NM_003118]
Cadherin 19   1.50↓ [GenBank:NM_021153]
Collagen IX-α3 1.59↑   [GenBank:NM_001853]
Cadherin 1.54↑   [GenBank:NM_001408]
COMP 1.52↑   [GenBank:NM_000095]
Collagen IV-α5   1.89↑ [GenBank:NM_000495]
Chondroitin sulfate PG4   1.64↑ [GenBank:NM_001897]
Matrix protein receptors    
HAS2 1.78↓   [GenBank:NM_005328]
CD44   2.34↓ [GenBank:NM_000610]
Integrins    
Integrin-α5 1.77↓   [GenBank:NM_002205]
Integrin-β4 1.64↓   [GenBank:AF011375]
Integrin-α6   2.34↓ [GenBank:NM_000210]
Integrin-β-like 1   2.07↓ [GenBank:NM_004791]
Integrin-β3   1.72↓ [GenBank:NM_000212]
Integrin-αE   1.70↓ [GenBank:NM_002208]