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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: a case-control study

Figure 6

Plateled-derived growth factor (PDGF) B immunoreactivity in pulmonary vessels in SScPAH, IPAH and PVOD. (Original magnification 200×). A) PDGF-B immunoreactivity in small vessel and capillaries in a patient with SScPAH. B) PDGF-B immunoreactivity in the intima layers of an arteriole with concentric laminar intimal fibrosis in a patient with SScPAH (see also 4B). C) PDGF-B immunoreactivity in a small vessel and (congested) capillaries in a PVOD patient. D) PDGF-B immunoreactivity in the basal side of the endothelium, the thickened intima and in smooth muscle cells in the hyperplastic media of an arteriole in a IPAH patient. E) PDGF-B immunoreactivity in stroma and endothelium of a plexiform lesion in an IPAH patient. In the center a glomeroid lesiom surrounded by vein-like branches (dilatation lesions).

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Arthritis Research & Therapy

ISSN: 1478-6362

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