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Figure 7 | Arthritis Research & Therapy

Figure 7

From: Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: a case-control study

Figure 7

Epidermal growth factor receptor (EGFR) immunoreactivity in pulmonary vessels in SScPAH, IPAH and PVOD. (Original magnification 200×). A) EGFR expression of alveolar epithelium surrounding a parenchymal arteriole (corner vessel) in a SScPAH patient, showing weak immunoreactivity of the media and endothelium. B) Weak EGFR immunoreactivity of endothelial cells in a SScPAH patient. C) EGFR expression in media and fibrotic intimal layer of an axial artery of a SScPAH patient. Left lower quadrant: parent artery. Center: glomeruloid lesion, surrounded by dilatation lesions (original magnification 100×). D) Plexiform lesion in an IPAH patient showing weak stromal EFGR expression.

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Arthritis Research & Therapy

ISSN: 1478-6362

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