Table 2 Deviated GO Biological Process gene categories of downregulated genes in peripheral blood of SLE patients
Gene category | List hits (n= 1,429) | Population hits (n= 13,802) | EASE score (<0.01) |
|---|---|---|---|
Sensory perception | 56 | 383 | 7.49 × 10-3 |
Perception of sound | 21 | 82 | 2.00 × 10-4 |
Hearing | 20 | 81 | 4.86 × 10-4 |
Response to radiation | 36 | 222 | 7.48 × 10-3 |
Response to light | 35 | 207 | 4.39 × 10-3 |
Calcium ion transport | 16 | 66 | 2.57 × 10-3 |
Macromolecule biosynthesis | 131 | 1,002 | 3.38 × 10-3 |
Protein biosynthesis | 90 | 650 | 3.38 × 10-3 |