Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage

Table 1 Clinical and radiological characteristics of the patients at the time of total joint replacement surgery

Patient	CRP, mg/L	ESR, mm/hour	ICRS grading score	Kellgren-Lawrence grading scale
1	0.3	9	3A	3
2	2.0	7	3A	3
3	1.2	5	3A	3
4	6.3	9	2B	2
5	5.4	19	2A	1
6	0.3	6	3A	3
7	8.1	23	3A	3
8	3.0	12	2A	2
9	10.0	9	3C	4
10	1.7	12	3B	4
11	4.3	12	3B	4

For the parameters of age, C-reactive protein (CRP) (normal range <5 mg/L), and erythrocyte sedimentation rate (ESR) (normal range <30 mm/hour), individual values are presented; x-ray grading of osteoarthritis was performed on the basis of the Kellgren-Lawrence scale [38], and macroscopic cartilage injury was graded according to the Hyaline Cartilage Lesion Classification System of the International Cartilage Repair Society (ICRS) [39]. The patient cohort consisted of 3 male and 8 female cartilage donors with a mean age of 69.6 ± 1.6 years and 3 left/8 right affected knee joints.

ISSN: 1478-6362