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Table 3 Comparison of differential gene expression values determined by relative quantitative-polymerase chain reaction and microarray analyses

From: Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases

Gene

RQ-PCRa

Microarraya

 

Affected

Unaffected

Affected

Unaffected

TNFAIP6

3.04

2.17

2.24

2.15

TNFSF10

1.50

1.37

1.58

1.33

MAP2K6

1.20

1.20

1.38

1.21

IL1RN

1.37

1.21

1.67

1.17

IFI27

1.20

2.01

7.24

6.21

ANXA3

3.18

1.82

2.79

2.43

CEACAM6

5.70

1.15

4.70

1.10

DEFA4

7.01

1.47

2.32

1.18

EIF2AK2

2.20

1.12

2.36

1.70

FCERA1

-1.82

-1.48

-1.76

-1.22

SYTL2

-1.93

-1.61

-1.49

-1.10

LGR6

-1.25

-1.13

-1.64

-1.11

KRTCAP2

-1.20

-1.20

-1.16

-1.07

LTK

1.02

1.21

2.32

1.06

FYN

1.23

1.19

-1.26

-1.01

  1. aFold change values indicating increased (positive value) or decreased (negative value) levels of gene expression in systemic autoimmune disease-affected or -unaffected twins compared with unrelated, matched controls. RQ-PCR, relative quantitative-polymerase chain reaction.
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Arthritis Research & Therapy

ISSN: 1478-6362

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