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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis

Figure 2

Antagonist treatment improves radiological indices of OA: X-ray results. (a) No surgery and saline treatment; (b) sham surgery and saline treatment; (c) ACLT and saline treatment; (d) ACLT and BQ-123 treatment; (e) ACLT and R-954 treatment; (f) ACLT and BQ-123+R-954 dual treatment. Blue arrows indicate tibial plateau, purple arrows indicate subchondral bone, and green arrows indicate osteophytes. Sagittal views. Scale bar, 1 cm.

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Arthritis Research & Therapy

ISSN: 1478-6362

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