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Table 3 OA radiological scores

From: Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis

Group number

Surgery

Treatment

Mean total radiological score

SD

1

None

Saline

0.25

0.50

2

Sham

Saline

1.16

0.75

3

ACLT

Saline

4.86

1.68

4

ACLT

BQ-123

2.83

1.47a

5

ACLT

R-954

2.50

1.22b

6

ACLT

BQ-123+R-954

2.67

1.03c

  1. Radiological scoring of the DX views of the knee joints [42, 43] indicated that antagonist treatment protected joint radiomorphology after ACLT. One-way ANOVA with Holm post-hoc: aP = 0.0214, ACLT/BQ-123 treatment versus ACLT/saline treatment; bP = 0.0020, ACLT/R-954 treatment versus ACLT/saline treatment; cP = 0.0125, ACLT/BQ-123+R-954 dual treatment versus ACLT/saline treatment.