From: Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis
Group number
Surgery
Treatment
Mean total radiological score
SD
1
None
Saline
0.25
0.50
2
Sham
1.16
0.75
3
ACLT
4.86
1.68
4
BQ-123
2.83
1.47a
5
R-954
2.50
1.22b
6
BQ-123+R-954
2.67
1.03c