Therapeutic effects of trichostatin A after the onset of arthritis in SKG mice. SKG mice were treated with dimethyl sulfoxide or trichostatin A on Day 22, when the mean clinical arthritis score was nearly 1.0 for 24 days. Results are expressed as the mean ± SE (DMSO group: n = 8, TSA group: n = 8). * P < 0.05. N.S., not significant.