Figure 7

Pain-related behavior in the different treatment groups over time. (A) Primary mechanical hyperalgesia obtained from mechanical thresholds at the inflamed knee joint. (B) Weight-bearing of arthritic animals as indicated by the relative body weight resting on the inflamed hindlimb. Data are presented as means ± SEM. *Differences between saline and dexamethasone. §Differences between saline and morphine. +Differences between morphine and dexamethasone. *P < 0.05; **P < 0.01; ***P < 0.001. AIA: antigen-induced arthritis.