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Table 3 Longitudinal associations between baseline clinical variables and 1-year MDHAQ pain, adjusted for age, gender, and baseline MDHAQ pain, among 157 RA patients in remission at baseline and 1 year

From: Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study

Variable Mean MDHAQ Pain (95% CI) P
Disease duration   0.02
≤3 years 1.6 (1.1, 2.2)  
4-11 years 2.0 (1.6, 2.5)  
≥12 years 2.4 (1.8, 3.0)  
Rheumatoid factor/cyclic citrullinated peptide status   0.77
Seropositive 1.9 (1.5, 2.4)  
Seronegative 2.1 (1.5, 2.6)  
Tender-joint count   0.36
0 2.1 (1.6, 2.5)  
1 1.7 (1.0, 2.5)  
≥2 1.8 (0.9, 2.6)  
Swollen-joint count   0.02
0 2.2 (1.8, 2.6)  
1 1.3 (0.3, 2.3)  
≥2 1.5 (1.0, 2.1)  
C-reactive protein   0.77
<0.7 mg/L 1.9 (1.4, 2.5)  
0.7-2.0 mg/L 2.0 (1.5, 2.5)  
≥2.1 mg/L 2.0 (1.5, 2.5)  
Patient global health assessment   0.03
<5 1.6 (0.9, 2.2)  
5-14 1.7 (1.1, 2.2)  
≥15 2.5 (2.0, 3.0)  
Sharp score   0.53
≤1 2.1 (1.4, 2.7)  
2-17 2.2 (1.6, 2.9)  
≥18 1.8 (1.1, 2.5)  
MDHAQ Function Scale   0.008
0 1.6 (1.0, 2.2)  
0.1-0.9 1.5 (1.0, 2.0)  
≥1.0 2.7 (2.1, 3.2)  
Mental Health Index 5   0.43
≤70 2.2 (1.7, 2.4)  
71-80 1.7 (1.1, 2.3)  
>80 1.9 (1.4, 2.4)  
MDHAQ Fatigue Scale   0.0001
<1.0 1.2 (0.7, 1.8)  
1.0-3.9 1.8 (1.3, 2.3)  
≥4.0 2.8 (2.3, 3.3)  
MDHAQ Sleep Problems Score   0.001
0 1.6 (1.1, 2.0)  
1 2.3 (1.8, 2.8)  
≥2 3.1 (2.2, 4.0)  
Arthritis Self-Efficacy Score   0.01
<78 2.2 (1.7, 2.7)  
78-87 2.3 (1.8, 2.8)  
≥88 1.4 (0.9, 1.9)  
Modified Charlson Index   0.35
≤1 1.9 (1.5, 2.3)  
>1 2.2 (1.6, 2.7)  
  1. MDHAQ, Multi-Dimensional Health Assessment Questionnaire; RA, rheumatoid arthritis. P values are from multivariable linear regression models.