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Table 3 Top 15 deviated functional categories of underexpressed genes in rheumatoid arthritis bone marrow compared with osteoarthritis bone marrow

From: Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis

Gene category List hits Population hits EASE score
(GO biological process) (Total = 733) (Total = 10,937)  
cell proliferation 139 1036 4.05E-16
   cell cycle 127 690 1.06E-26
   mitotic cell cycle 97 329 2.78E-37
   M phase 48 157 3.98E-19
   nuclear division 47 151 4.40E-19
   mitosis 44 121 7.91E-21
   regulation of mitosis 11 26 3.37E-06
   regulation of cell cycle 64 384 1.83E-11
   cell cycle checkpoint 15 35 1.98E-08
   cytokinesis 26 95 1.83E-09
DNA replication and chromosome cycle 52 186 8.28E-19
   DNA replication 40 146 2.96E-14
   DNA dependent DNA replication 23 75 1.86E-09
DNA metabolism 85 517 1.02E-14
   nucleocytoplasmic transport 21 97 5.06E-06
  1. EASE, Expression Analysis Systematic Explorer software, Version 2.0; Gene Ontology database; GO, gene ontology.