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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Analysis of IL-17+cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

Figure 1

In situ analysis and quantification of IL-17+ cells in patients with ankylosing spondylitis or osteoarthritis. (a) In situ analysis of IL-17+ cells in facet joints of ankylosing spondylitis (AS) (top) and osteoarthritis (OA) (bottom) patients. The specificity of IL-17 staining (top) is shown by blocking the anti-IL-17 antibody with recombinant IL-17 (rIL-17) (middle). (b) and (c) The frequency of IL-17-secreting mononuclear cells and cells with polysegmental nuclei in the bone marrow of AS facet joints was significantly higher in AS than in OA facet joints. *P < 0.001.

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