Table 2 Performance characteristics of multiplex-assayed autoantibody profiles in the diagnosis of rheumatoid arthritis
From: Novel multiplex technology for diagnostic characterization of rheumatoid arthritis
Number of positive biomarkers* | PPV | NPV | Sensitivity | Specificity |
|---|---|---|---|---|
1+ markers | 79.5% | 92.6% | 96.7% | 62.5% |
2+ markers | 91.8% | 89.7% | 93.3% | 87.5% |
3+ markers | 95.3% | 79.8% | 84.2% | 93.8% |
4+ markers | 95.9% | 61.1% | 59.2% | 96.3% |