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Table 4 Causes of infliximab discontinuation in ATIpos and ATIneg patientsa

From: Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases

Cause of discontinuation

ATIpos (n= 18)

ATIneg (n= 41)

Treatment failure

  

   Primary failure

2 (11%)

23 (56%)

   Secondary failure

3 (17%)

8 (20%)

Infusion reactions

9 (50%)

1 (2%)

Adverse events

1 (5.5%)

6 (15%)

Other

1 (5.5%)

2 (5%)

Lost to follow-up

2 (11%)

1 (2%)

  1. aATI: antibodies toward infliximab; ATIpos: ATI detected at least once during follow-up; ATIneg: ATI not detected. All data are number of patients (%).