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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach

Figure 3

Serum IgG reactivity to lamin in serum of giant cell arteritis patients. Protein extract is from vascular smooth muscle cells (VSMCs). (A) IgG reactivity to lamin in five different pools of sera from three giant cell arteritis patients each (P1 to P5) and one pool from twelve healthy controls (HC). (B) Lamin spots are expressed in 3-D views for one representative sera pool of giant cell arteritis patients (top) and the HC pool (bottom). (C) Proteome of VSMCs showing the localisation of lamin spots displayed in (A).

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