SNP | CHI3L1position | Controls (n = 605) | F df = 603 | P-value | RA age ≤ 65 years (n = 238) | F Df = 236 | P-value |
---|---|---|---|---|---|---|---|
rs6691378 | g.-1371G/A | Serum YKL-40 ng/ml | Â | Â | serum YKL-40 ng/ml | Â | Â |
 | G/G | 46 (44 to 48) | 6.63 | 0.0014 | 67 (61 to 74) | 2.85 | 0.06 |
 | G/A | 54 (50 to 59) |  |  | 77 (62 to 95) |  |  |
 | A/A | 47 (34 to 68) |  |  | 151 (71 to 323) |  |  |
rs10399931 | g.-329C/T | Â | Â | Â | Â | Â | Â |
 | C/C | 56 (53 to 58) | 83.13 | < 2.2e-16 | 80 (71 to 89) | 12.34 | 8.0e-06 |
 | C/T | 40 (38 to 42) |  |  | 61 (53 to 70) |  |  |
 | T/T | 25 (22 to 29) |  |  | 35 (24 to 49) |  |  |
rs10399805 | g.-247G/A | Â | Â | Â | Â | Â | Â |
 | G/G | 45 (44 to 47) | 7.47 | 6.3e-3 | 67 (61 to 74) | 2.69 | 0.07 |
 | G/A | 54 (50 to 59) |  |  | 76 (61 to 94) |  |  |
 | A/A | 48 (34 to 68) |  |  | 151 (71 to 323) |  |  |
rs4950928 | g.-131C/G | Â | Â | Â | Â | Â | Â |
 | C/C | 56 (53 to 58) | 102.32 | < 2.2e-16 | 81 (73 to 90) | 18.91 | 2.4e-08 |
 | C/G | 38 (38 to 40) |  |  | 59 (51 to 68) |  |  |
 | G/G | 25 (22 to 28) |  |  | 31 (22 to 43) |  |  |
rs7515776 | g.+48A/T | Â | Â | Â | Â | Â | Â |
 | A/A | 46 (44 to 48) | 7.02 | 9.7e-3 | 67 (61 to 74) | 1.76 | 0.17 |
 | A/T | 54 (50 to 59) |  |  | 77 (62 to 95) |  |  |
 | T/T | 48 (33 to 70) |  |  | 119 (62 to 231) |  |  |
rs1538372 | g.+1219G/A | Â | Â | Â | Â | Â | Â |
 | G/G | 56 (53 to 59) | 46.93 | < 2.2e-16 | 78 (68 to 89) | 7.58 | 6.5e-3 |
 | G/A | 43 (41 to 45) |  |  | 69 (60 to 78) |  |  |
 | A/A | 34 (30 to 37) |  |  | 45 (34 to 57) |  |  |
rs2071579 | g.+2117G/C | Â | Â | Â | Â | Â | Â |
 | C/C | 56 (52 to 59) | 21.91 | 6.5e-10 | 72 (62 to 84) | 6.31 | 0.0022 |
 | C/G | 47 (44 to 49) |  |  | 76 (67 to 86) |  |  |
 | G/G | 39 (36 to 42) |  |  | 52 (43 to 62) |  |  |
rs880633 | g.+2950C/T | Â | Â | Â | Â | Â | Â |
 | C/C | 56 (52 to 59) | 21.91 | 6.7e-10 | 72 (62 to 84) | 6.31 | 0.0022 |
 | C/T | 47 (44 to 49) |  |  | 76 (67 to 86) |  |  |
 | T/T | 39 (36 to 42) |  |  | 52 (43 to 62) |  |  |