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Table 2 Modification of mean DAS28 and TES of the 77 RA patients and patient response percentages according to EULAR criteria at baseline (T0) and after three months (T3) and six months (T6) of anti-TNF therapya

From: Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis

Outcome measure

T0

T3

T6

P value

Mean DAS28 (± SD)

5.2 ± 1.2

3.9 ± 1.6

3.8 ± 1.4

T0 vs. T3 < 0.0001

EULAR response

-

  

-

   Good (%)

 

25

31.8

 

   Moderate (%)

 

38.5

25

 

   None (%)

 

36.6

43.2

 

Mean overall patient TES (± SD)

33.4 ± 21.9

40.3 ± 22.8

40.5 ± 22.4

NS

  1. aDAS28: disease activity score in 28 joints; EULAR: European League Against Rheumatism; NS: not significant; PIP: proximal interphalangeal; RA: rheumatoid arthritis; TES: total erosion score; TNF, tumor necrosis factor.