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Table 1 Combined incidence of arthritis in first nine generations of IIJ straina

From: Characterization of a novel and spontaneous mouse model of inflammatory arthritis

  

Progeny

Phenotype of parentsb

Total

Female

Male

Male × Female, n (%)

   

   AR × AR

159 of 463 (34%)

84 of 207 (41%)

75 of 256 (29%)

   AR × NAR

77 of 273 (28%)

41 of 120 (34%)

36 of 153 (24%)

   NAR × AR

39 of 99 (39%)

22 of 53 (42%)

17 of 46 (37%)

   NAR × NAR

29 of 97 (30%)

15 of 44 (34%)

14 of 53 (26%)

Overall, n (%)

304 of 932 (33%)

162 of 424 (38%)

142 of 508 (28%)

  1. aProgeny were considered arthritic when they maintained a score of 2 (see Materials and methods for details) on the same paw for two consecutive readings. Results were combined based on phenotype of parents regardless of generation. bArthritic (AR) or nonarthritic (NAR); all were intercrosses between littermates.
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Arthritis Research & Therapy

ISSN: 1478-6362

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