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Table 1 Number of aPL antibody positive sera investigating 85 APS patients, 65 DC patients, and 79 NHS in ELISA and in the MLDA

From: Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay

  ELISA MLDA ELISA or MDLA
  anti-CL anti-β2 GPI anti-CL or anti-β2 GPI anti-PS anti-PI anti-CL anti-β2 GPI anti-PS, anti-PI, anti-CL or anti-β2 GPI  
  IgG IgM IgG IgM   IgG IgM IgG IgM IgG IgM IgG IgM   
APS
n = 85
45 32 27 33 50 28 17 7 3 39 33 31 27 57 63
DC
n = 65
1 1 0 0 1 1 0 0 0 2 3 0 3 7 8
NHS
n = 79
1 0* 0 4 5 1 1 0 0 2 6* 0 5 8 12
  1. * P < 0.05 for the comparison of ELISA and MLDA
  2. APS, antiphospholipid syndrome; anti-β2 GPI, anti-beta2-glycoprotein I; anti-CL, anti-cardiolipin; anti-PI, anti-phosphatidylinositol; anti-PS, anti-phosphatidylserine; DC, disease controls; ELISA, enzyme-linked immunosorbent immunoassay; MLDA, multi-line dot assay; NHS, normal healthy subjects.