From: Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay
Sensitivity | 95% CI | Specificity | 95% CI | +LR | 95% CI | -LR | 95% CI | |
---|---|---|---|---|---|---|---|---|
anti-PS IgG | 32.9 | 23.1 to 44.0 | 98.6 | 95.1 to 99.8 | 23.7 | 5.8 to 97.1 | 0.7 | 0.6 to 0.8 |
anti-PS IgM | 20.0 | 12.1 to 30.1 | 99.3 | 96.2 to 100.0 | 28.8 | 3.9 to 212.6 | 0.8 | 0.7 to 0.9 |
anti-PI IgG | 8.2 | 3.4 to 16.2 | 100.0 | 97.5 to 100.0 | ∞ | 0.9 | 0.9 to 1.0 | |
anti-PI IgM | 3.5 | 0.7 to 10.0 | 100.0 | 97.5 to 100.0 | ∞ | 1.0 | 0.9 to 1.0 | |
anti-CL IgG | 45.9 | 35.0 to 57.0 | 97.2 | 93.0 to 99.3 | 16.5 | 6.1 to 44.6 | 0.6 | 0.5 to 0.7 |
anti-CL IgM | 38.8 | 28.4 to 50.0 | 93.8 | 88.5 to 97.1 | 6.2 | 3.1 to 12.3 | 0.6 | 0.6 to 0.8 |
anti-β2 GPI IgG | 36.5 | 26.7 to 47.6 | 100.0 | 97.5 to 100.0 | ∞ | 0.6 | 0.5 to 0.8 | |
anti-β2 GPI IgM | 31.8 | 22.1 to 42.8 | 94.4 | 89.4 to 97.6 | 5.7 | 2.7 to 12.1 | 0.7 | 0.6 to 0.8 |