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Table 1 Spearman's rank test correlations of 4-HNE microscopic scores in synovial tissue pre/post anti TNF-α therapy with clinical parameters

From: Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

4-HNE

r-value

Pvalue

tpO2

-0.60

0.008

DAS28-CRP

0.53

0.02

TJC-28

0.49

0.03

SJC-28

0.50

0.03

VAS

0.48

0.04

  1. DAS28-CRP, 28-joint count disease activity score using C-reactive protein; 4-HNE, 4-hydroxy-2-nonenal; SJC-28, swollen joint count for 28 joints; TJC-28, tender joint count for 28 joints; tpO2, in vivo tissue oxygen tension; VAS, visual analogue scale.