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Table 1 Spearman's rank test correlations of 4-HNE microscopic scores in synovial tissue pre/post anti TNF-α therapy with clinical parameters

From: Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

4-HNE r-value Pvalue
tpO2 -0.60 0.008
DAS28-CRP 0.53 0.02
TJC-28 0.49 0.03
SJC-28 0.50 0.03
VAS 0.48 0.04
  1. DAS28-CRP, 28-joint count disease activity score using C-reactive protein; 4-HNE, 4-hydroxy-2-nonenal; SJC-28, swollen joint count for 28 joints; TJC-28, tender joint count for 28 joints; tpO2, in vivo tissue oxygen tension; VAS, visual analogue scale.