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Table 2 Spearman's rank test correlations of 4-HNE synovial tissue pre/post anti TNF-α therapy with synovial inflammation and angiogenesis

From: Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

4-HNE r-value Pvalue
CD4 ll 0.60 0.04
CD8 sl 0.70 0.001
CD20 sl 0.68 0.04
CD68 ll 0.47 0.04
VEGF bv 0.63 0.01
  1. bv, blood vessel; CD4 and CD8, T-cell markers; CD20, B-cell marker; CD68, marker of macrophages; 4-HNE, 4-hydroxy-2-nonenal; ll, lining layer; sl, sublining layer; VEGF, vascular endothelial growth factor.