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Table 2 Spearman's rank test correlations of 4-HNE synovial tissue pre/post anti TNF-α therapy with synovial inflammation and angiogenesis

From: Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

4-HNE

r-value

Pvalue

CD4 ll

0.60

0.04

CD8 sl

0.70

0.001

CD20 sl

0.68

0.04

CD68 ll

0.47

0.04

VEGF bv

0.63

0.01

  1. bv, blood vessel; CD4 and CD8, T-cell markers; CD20, B-cell marker; CD68, marker of macrophages; 4-HNE, 4-hydroxy-2-nonenal; ll, lining layer; sl, sublining layer; VEGF, vascular endothelial growth factor.