Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

Table 3 Spearman's rank test correlations of mitochondrial point mutations pre/post anti TNF-α therapy with clinical parameters

Mitochondrial point mutations	r-value	Pvalue
DAS28-CRP	0.83	0.01
CRP (mmg/L)	0.77	0.02
ESR (mm/hr)	0.73	0.04

CRP, C-reactive protein; DAS28-CRP, 28-joint count disease activity score using C-reactive protein; ESR, erythrocyte sedimentation rate.

ISSN: 1478-6362