Table 2 Allele and genotype frequencies in a case-control cohort of patients with RA
From: Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis
dbSNP identity | Allele/ Genotype | Numbers of patients with RA (%) | Numbers of controls (%) | Fisher's P-value | Odds ratio (95% CI) |
|---|---|---|---|---|---|
rs9505298 | A | 75 (0.144) | 10 (0.032) | 1.83E-07 | 5.157303 (2.624041 to 10.136190) |
| Â | G | 445 (0.856) | 306 (0.968) | Â | 5.157303 (2.624041 to 10.136190) |
| Â | AA | 1 (0.004) | 0 (0.000) | 3.13E-07 | Â |
| Â | AG | 73 (0.281) | 10 (0.063) | Â | Â |
| Â | GG | 186 (0.715) | 148 (0.937) | Â | Â |
rs41302895 | A | 64 (0.120) | 9 (0.028) | 3.32E-06 | 4.725546 (2.317854 to 9.634252) |
| Â | T | 468 (0.880) | 311 (0.972) | Â | 4.725546 (2.317854 to 9.634252) |
| Â | AA | 1 (0.004) | 0 (0.000) | 9.11E-06 | Â |
| Â | AT | 62 (0.233) | 9 (0.056) | Â | Â |
| Â | TT | 203 (0.763) | 151 (0.944) | Â | Â |
rs1225936 | A | 24 (0.045) | 2 (0.006) | 0.001438 | 7.494071 (1.759029 to 31.927328) |
| Â | C | 506 (0.955) | 316 (0.994) | Â | 7.494071 (1.759029 to 31.927328) |
| Â | AC | 24 (0.091) | 2 (0.013) | 0.001201 | 7.817427 (1.821928 to 33.542572) |
| Â | CC | 241 (0.909) | 157 (0.987) | Â | 7.817427 (1.821928 to 33.542572) |
rs1225938 | A | 270 (0.509) | 190 (0.594) | 0.016879 | 0.710526 (0.536647 to 0.940745) |
| Â | G | 260 (0.491) | 130 (0.406) | Â | 0.710526 (0.536647 to 0.940745) |
| Â | AA | 53 (0.200) | 52 (0.325) | 0.013717 | Â |
| Â | AG | 164 (0.619) | 86 (0.537) | Â | Â |
| Â | GG | 48 (0.181) | 22 (0.138) | Â | Â |
rs372578 | A | 224 (0.424) | 109 (0.341) | 0.015688 | 1.426364 (1.068889 to 1.903392) |
| Â | G | 304 (0.576) | 211 (0.659) | Â | 1.426364 (1.068889 to 1.903392) |
| Â | AA | 45 (0.170) | 21 (0.131) | 0.029497 | Â |
| Â | AG | 134 (0.508) | 67 (0.419) | Â | Â |
| Â | GG | 85 (0.322) | 72 (0.450) | Â | Â |
rs443861* | A | 117 (0.221) | 48 (0.150) | 0.011538 | 1.605327 (1.109766 to 2.322179) |
| Â | G | 413 (0.779) | 272 (0.850) | Â | 1.605327 (1.109766 to 2.322179) |
| Â | AA | 6 (0.023) | 3 (0.019) | 0.016509 | Â |
| Â | AG | 105 (0.396) | 42 (0.263) | Â | Â |
| Â | GG | 154 (0.581) | 115 (0.719) | Â | Â |
rs408014 | A | 303 (0.574) | 211 (0.659) | 0.013531 | 0.695671 (0.521353 to 0.928274) |
| Â | G | 225 (0.426) | 109 (0.341) | Â | 0.695671 (0.521353 to 0.928274) |
| Â | AA | 86 (0.326) | 72 (0.450) | 0.03402 | Â |
| Â | AG | 131 (0.496) | 67 (0.419) | Â | Â |
| Â | GG | 47 (0.178) | 21 (0.131) | Â | Â |
rs9392189* | A | 116 (0.221) | 103 (0.322) | 0.001239 | 0.598991 (0.438317 to 0.818563) |
| Â | G | 408 (0.779) | 217 (0.678) | Â | 0.598991 (0.438317 to 0.818563) |
| Â | AA | 16 (0.061) | 18 (0.113) | 0.007146 | Â |
| Â | AG | 84 (0.321) | 67 (0.419) | Â | Â |
| Â | GG | 162 (0.618) | 75 (0.469) | Â | Â |
rs2743992* | A | 230 (0.437) | 163 (0.509) | 0.041455 | 0.748425 (0.566338 to 0.989055) |
| Â | G | 296 (0.563) | 157 (0.491) | Â | 0.748425 (0.566338 to 0.989055) |
| Â | AA | 43 (0.163) | 44 (0.275) | 0.022536 | Â |
| Â | AG | 144 (0.548) | 75 (0.469) | Â | Â |
| Â | GG | 76 (0.289) | 41 (0.256) | Â | Â |