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Table 6 Allele and genotype frequencies in a case-control cohort of patients with RA

From: Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis

dbSNP identity

Allele/

Genotype

No. of patients with RA (%)

No. of controls (%)

Fisher's P-value

rs2277105

C

1581 (0.840)

1512 (0.848)

0.491098

 

O(freq)

19 (0.010)

12 (0.007)

 
 

T

283 (0.150)

260 (0.146)

 
 

CC

670 (0.719)

650 (0.734)

0.549842

 

CT

241 (0.259)

212 (0.239)

 
 

TT

21 (0.023)

24 (0.027)

 

rs11962800

A

1568 (0.831)

1523 (0.853)

0.173781

 

O(freq)

15 (0.008)

11 (0.006)

 
 

G

304 (0.161)

251 (0.141)

 
 

AA

656 (0.701)

656 (0.740)

0.184145

 

AG

256 (0.274)

211 (0.238)

 
 

GG

24 (0.026)

20 (0.023)

 

rs443861

A

357 (0.190)

275 (0.154)

0.00832

 

O(freq)

19 (0.010)

12 (0.007)

 
 

G

1507 (0.800)

1497 (0.839)

 
 

AA

51 (0.055)

26 (0.029)

0.01011

 

AG

255 (0.274)

223 (0.252)

 
 

GG

626 (0.672)

637 (0.719)

 

rs369086

A

485 (0.257)

460 (0.258)

0.510123

 

O(freq)

18 (0.010)

11 (0.006)

 
 

G

1381 (0.733)

1314 (0.736)

 
 

AA

61 (0.065)

71 (0.080)

0.260584

 

AG

363 (0.389)

318 (0.359)

 
 

GG

509 (0.546)

498 (0.561)

 
  1. 898 controls and 951 RA cases observed. RA, rheumatoid arthritis; SNP, single nucleotide polymorphism