From: Characterization of a novel and spontaneous mouse model of inflammatory arthritis
Type of drug | Name of drug | Use |
---|---|---|
Drugs that affect symptoms of the disease (analgesics) | Acetaminophen Aspirin | Relieves pain Reduces inflammation and relieves pain |
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) | Diclofenac Diflunisal, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, meclofenamate, mefenamic acid, meloxicam, nabumetone, naproxen, oxaprozin, phenylbutazone, piroxicam, sulindac, tolmetin | Reduces inflammation and relieves pain All NSAIDs treat the symptoms and decrease inflammation but do not alter the course of the disease |
COX-2 inhibitors | Celecoxib, valdecoxib | Reduces inflammation and relieves pain |
Narcotic/analgesics | Propoxyphene Tramadol | Relieves pain Relieves pain |
Corticosteroids | Methylprednisolone, prednisone, injectable corticosteroids | Suppresses inflammation in severe organ disease or life-threatening disease |
Disease-modifying antirheumatic drugs (DMARDs)a | Auranofin (oral gold), cyclosporine, gold salts (injectable), hydroxychloroquine, leflunomide, methotrexate, penicillamine, sulfasalazine | All DMARDs can slow progression of joint damage as well as gradually decrease pain and swelling |
Biologics | Â | Â |
   Anti-TNF compounds | Adalimumab, etanercept, infliximab, certolizumab, golimumab | Suppresses inflammation and inhibit the progress of joint damage |
   IL-1 inhibitor | Anakinra | Treats moderate to severe RA in people who do not respond to DMARDs |
   B-cell-depleting agent | Rituximab | Treats RA unresponsive to TNF inhibitors |
   T-cell co-stimulation antagonist | Abatacept | Treats RA unresponsive to DMARD therapy |
   IL-6 antagonist | Tocilizumab | Treats RA unresponsive to TNF inhibitors |