Variables | T0 (n= 700) | T5 (n= 442) |
---|---|---|
Sex, f/m | 481/219 | 301/141 |
Age at onset of symptoms (years) | 55.2 (14.3) | 55.1 (14.2) |
Duration of symptoms at inclusion (mo) | 6.6 (3.3) | 6.7 (3.2) |
RF, n (%) | 489 (76.4) | na |
ANA, n (%) | 130 (25.0) | na |
Anti-CCP, n (%) | 373 (67.8) | na |
SE, n (%) | 330 (56.9) | na |
PTPN22 Tvariant, n (%) | 167 (34.0) | na |
ESR (mm) | 31.5 (23.7) | 20.0 (19.9)*** |
CRP (mg/l) | 22.0 (24.6) | 11.1 (14.3)*** |
DAS281 | 4.8 (1.4) | 3.2 (1.3)*** |
HAQ1 | 0.9 (0.6) | 0.6 (0.52)*** |
Tender joints1 | 6.7 (5.8) | 2.6 (3.7)*** |
Swollen joints1 | 7.4 (5.2) | 3.2 (4.1)*** |
VAS pain (mm)1 | 44.5 (25.2) | 28.7 (20.7)*** |
VAS global (mm) 1 | 45.3 (24.9) | 29.8 (20.6)*** |
AUC DAS28 (6 mo)1,2 | - | 25.8 (7.1) |
AUC DAS28 (12 mo)1,2 | - | 47.2 (13.5) |
AUC DAS28 (24 mo)1,2 | - | 87.5 (26.0) |
Extra-articular disease, n (%)3 | - | 21 (3.0) |
Presence of nodules, n (%) | - | 78 (20.7) |